Sodium Balance in Maintenance Hemodialysis

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Sodium Balance in Maintenance Hemodialysis

Sodium is the principal solute in the extracellular compartment and the major component of serum osmolality. In normal persons in the steady state, sodium homeostasis is achieved by a balance between the dietary intake and the urinary output of sodium, whereas in intermittent hemodialysis patients, sodium balance depends on dietary intake and sodium removal during hemodialysis. Thus, the main g...

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Dialysate sodium, serum sodium and mortality in maintenance hemodialysis.

BACKGROUND Individuals with end-stage kidney disease appear to have stable pre-dialysis serum sodium concentrations over time, with lower values associating with increased mortality. Dialysate sodium concentrations have increased over many years in response to shorter treatments, but the relationship between serum sodium, dialysate sodium and outcomes in chronic hemodialysis patients has not ye...

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Dialysate sodium and sodium gradient in maintenance hemodialysis: a neglected sodium restriction approach?

BACKGROUND A higher sodium gradient (dialysate sodium minus pre-dialysis plasma sodium) during hemodialysis (HD) has been associated with sodium loading; however, its role is not well studied. We hypothesized that a sodium dialysate prescription resulting in a higher sodium gradient is associated with increases in interdialytic weight gain (IDWG), blood pressure (BP) and thirst. METHODS We co...

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Effect of sodium balance and the combination of ultrafiltration profile during sodium profiling hemodialysis on the maintenance of the quality of dialysis and sodium and fluid balances.

Excessive sodium gain is a major hindrance of sodium profiling hemodialysis (HD) that offsets the benefit in reducing intradialytic hypotension-related discomforts (IHD). Patients who showed frequent IHD (>30% of the sessions; n = 11) were enrolled in a prospective study that consisted of two phases. In the phase 1 study, eight treatment modalities were evaluated: Conventional HD (control), sod...

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Effect of dialysate sodium concentration and sodium gradient on patients with maintenance hemodialysis

Backgrounds: Patients with maintenance hemodialysis (MHD) have a high risk of cardiovascular disease, which is the leading cause of morbidity and mortality. The aim of the present study was to explore the relationship between the sodium gradient and the water load of MHD patients. Methods: Eighty one MHD patients were selected in the study. The serum sodium concentration, sodium gradient, inter...

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ژورنال

عنوان ژورنال: Electrolytes & Blood Pressure

سال: 2012

ISSN: 1738-5997,2092-9935

DOI: 10.5049/ebp.2012.10.1.1